Porcine reproductive and respiratory syndrome (PRRS)

VISTA PREVIA

Porcine reproductive and respiratory syndrome (PRRS)

LANGUAGE: ENGLISH

Author(s): Ramírez, Alejandro
Release date: 2015
ISBN: 978-84-16315-20-8
Pages: 112
Binding: Hardcover. Spiral-bound
Format: 11 x 20

The objective of this guide is to provide a practical summary regarding current knowledge and understanding of porcine reproductive and respiratory syndrome (PRRS). The information presented is focused on clinically relevant and practical information to help field veterinarians and farm team personnel interested in animal health.


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1. Introduction

Brief history
Agent
Structure

  • Small
  • Enveloped
  • Shape
  • Single strand RNA
  • Nine open read fragments
  • (ORFs 1a, 1b, 2, 2b, 3, 4, 5, 6, and 7)

2. Economic impact
Economic impact of PRRS

3. Clinical signs
Clinical signs of PRRS

  • General clinical signs
  • Reproductive clinical signs
  • Respiratory clinical signs


4. Pathogenesis
Tissue tropism
Lesions

  • Lung
  • Lymph nodes
  • Other lesions


5. Epidemiology
PRRSv epidemiologic characteristics

  • Highly infectious
  • Low transmission potential

Incubation time
Routes of transmission
Persistent infections
Mutations and quasispecies
Subpopulations


6. Immunity
Introduction
Innate immunity

  • Definitions

Adaptive cell-mediated immunity
Humoral immunity
Maternal immunity
Cross-protection


7. Diagnostic tests
Agent detection

  • Best samples
  • Histopathology
  • Virus isolation (VI)
  • Polymerase chain reaction (PCR)
  • Direct fluorescent antibody test (FA)
  • Immunohistochemistry (IHC)
  • Genetic sequencing
  • Restriction fragment length polymorphism
  • (RFLP)

Antibody detection

  • Enzyme-linked immunosorbent assay (ELISA)
  • Serum virus neutralization (SVN or SN)
  • Indirect fluorescent antibody assay (IFA)
  • Immunoperoxidase monolayer assay (IPMA)

8. Herd monitoring
Monitoring program design

  • Serum
  • Oral fluids
  • Herd classification
  • Important notes regarding breeding herd
  • classification


9. Biosecurity
PRRSv resistance in the environment

  • Environmental stability
  • Water and manure
  • Pork meat
  • Vectors

Biosecurity practices
PADRAP


10. Control and elimination
Role of vaccines

  • Killed vaccines
  • Modified live virus (MLV) vaccines

Basics of control

  • McRebel program
  • Herd closure
  • Homogenize

PrRsv elimination

  • AASV position statement regarding PRRS
  • Depopulation and repopulation (depop-repop)
  • Test and removal
  • Herd rollover
  • Regional elimination

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Porcine reproductive and respiratory syndrome (PRRS)

Porcine reproductive and respiratory syndrome (PRRS)

LANGUAGE: ENGLISH

Author(s): Ramírez, Alejandro
Release date: 2015
ISBN: 978-84-16315-20-8
Pages: 112
Binding: Hardcover. Spiral-bound
Format: 11 x 20

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