Diseases of Swine 11th Edition
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Diseases of Swine 11th Edition

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Diseases of Swine has been the definitive reference on swine health and disease for over 60 years. This new edition has been completely revised to include the latest information, developments, and research in the field. Now with full color images throughout, this comprehensive and authoritative resource has been redesigned for improved consistency and readability, with a reorganized format for more intuitive access to information.

Jeffrey J. Zimmerman


Professor of Disease Ecology in the Department of Veterinary Diagnostic and Production Animal Medicine at Iowa State University in Ames, Iowa, USA.

Locke A. Karriker


Professor of Veterinary Diagnostic and Production Animal Medicine and Director of the Swine Medicine Education Center at Iowa State University in Ames, Iowa, USA.

Alejandro Ramirez


Associate Professor of Veterinary Diagnostic and Production Animal Medicine at Iowa State University in Ames, Iowa, USA.

Kent J. Schwartz


Clinical Professor and Diagnostician at the Iowa State University Veterinary Diagnostic Laboratory in Ames, Iowa, USA.

Gregory W. Stevenson


Professor of Veterinary Pathology and Diagnostic Pathologist at Iowa State University in Ames, Iowa, USA.

Jianqiang Zhang


Associate Professor of Veterinary Diagnostic and Production Animal Medicine at Iowa State University in Ames, Iowa, USA.

Contributing Authors

Editors' Note


1 Herd Evaluation

Records, benchmarks, four circles approach, diagnostic approaches, prioritizing interventions, reporting, blood sample collection, oral fluid collection.

2 Behavior and Welfare

Definitions of welfare, normal vs abnormal behaviors, maternal behaviors, minimizing welfare impact of invasive procedures, feeding and drinking behaviors, human interactions, behavior responses due to disease, recognizing pain, vices, objective measures of pain.

3 Genetics and Health

Genetic influences on mortality, disease resistance, immune response and sow productive lifetime, with a summary of recent genetic advances.

4 Effect of Environment on Health

Evaluation of the environment, recommended air temperatures, minimum ventilation rates, space recommendations, water requirements, feeder space recommendations. Investigation of death due to ventilation failure. Impact of noise levels and stray voltage.

5 Differential Diagnosis of Diseases

Diarrhea, vomiting, rectal prolapses, respiratory distress, anemia, sneezing, skin, neurologic, lameness, reproductive, congenital, zoonotic, vesicular lesions, urinary tract.

6 Diagnostic Tests, Test Performance, and Considerations for Interpretation

How diagnostic tests are performed, advantages and disadvantages. PCR testing considerations including quantitative interpretation. Appropriate uses of genetic sequencing. Descriptions of metagenomics technology.

7 Optimizing Diagnostic Value and Sample Collection

Developing the diagnostic plan, diagnostic sample selection, pig necropsy, necropsy safety, knife sharpening.

8 Collecting Evidence and Establishing Causality

Sources of variation in test results, sensitivity and specificity, testing in series or parallel, selecting test cutof values, selecting appropriate sample size, screening and confirmatory tests. Evidence-based medicine, establishing baselines, evaluating interventions.

9 Disease Control, Prevention, and Elimination

Routes of transmission, ecology of disease, pathogen cycles, biological risk management, principles of biosecurity, biocontainment, bioexclusion.

10 Drug Pharmacology, Therapy and Prophylaxis

Antimicrobial drug classes, considerations for treatment, residue avoidance, establishing treatment regimens, limiting the development of resistance, parasiticides, impact of drug treatment on immunity, bacteriophages, probiotics, hormones, and anti-inflammatory drugs.

11 Anesthesia and Surgical Procedures

Injectable anesthetic agents, sedation, catheterization techniques, epidural injection, anesthetic drug combinations, reversal agents and pain management. Surgical procedures including castration, correction of prolapses, cystostomy procedures, cesarean section, fracture repair, tusk removal, abdominal and musculoskeletal procedures.

12 Pre-Harvest Food Safety, Zoonotic Diseases and the Human Health Interface

Physical, chemical, and biologic hazards, drug residues, MRSA, feed safety, certification programs.

13 Special Considerations for Show and Pet Pigs

Dynamics of the show pig industry, biosecurity, zoonotic implications, vaccination protocols, behavior and training, ethics, teeth trimming, hoof trimming, obesity, and parasites.


14 Cardiovascular and Hemopoietic System

Anatomy, pathophysiology, mulberry heart disease, anemia, shock, clinical pathology.

15 Digestive System

Interactions of flora, nutrition, immune system, anatomy, pathophysiology, gastric ulcers, hemorrhagic bowel syndrome, prolapses, hernias.

16 Immune System

Innate and adaptive immunity. Cellular, humoral, mucosal and passive immune mechanisms. Stress, nutrition, immunosuppression, vaccination. Lactogenic immunity.

17 Integumentary System: Skin, Foot, and Claw

Pathophysiology of skin, infectious conditions, vesicles, ear necrosis, porcine dermatopathy and nephropathy syndrome. Pathophysiology of coronary band, foot and claw. Traumatic and nutritional contributors to foot and claw lesions.

18 Mammary System

Structure and development, physiology of lactation, physiology of maternal immunity, pathophysiology of lactation dysfunction, mastitis, dysgalactia, and risk factors.

19 Nervous and Locomotor System

Pathophysiology of nervous system, muscle, bone, joint and eye. Congenital abnormalities, splayleg, congenital tremor, myopathy, porcine stress syndrome, arthritis, metabolic bone disease, rickets, osteochondrosis.

20 Reproductive System

Control of estrus, pregnancy, and parturition. Pregnancy diagnosis, dystocia, prolapse, discharge, male reproductive function and semen quality. Laboratory investigation of abortion and reproductive failure.

21 Respiratory System

Anatomy, structure, function, pathophysiology.

22 Urinary System

Anatomy, structure, function, pathophysiology


23 Overview of Viruses

General characteristics of viruses, virus taxonomy, detection and characterization of viruses.

24 Adenoviruses

25 African Swine Fever Virus

26 Anelloviruses

Torque teno sus viruses

27 Astroviruses

28 Bunyaviruses

Akabane virus, Lumbo virus, Oya virus, Tahyna virus.

29 Caliciviruses

Porcine noroviruses, porcine sapoviruses, St-Valérien virus, vesicular exanthema of swine virus.

30 Circoviruses

31 Coronaviruses

Hemagglutinating encephalomyelitis virus, porcine deltacoronavirus, porcine epidemic diarrhea virus, porcine respiratory coronavirus, porcine torovirus, transmissible gastroenteritis virus.

32 Filovirus

Reston ebolavirus, Zaire ebolavirus.

33 Flaviviruses

Japanese encephalitis virus, Murray Valley encephalitis virus, West Nile virus, other flaviviruses.

34 Hepatitis E Virus

35 Herpesviruses

Malignant catarrhal fever (ovine herpesvirus 2), porcine cytomegalovirus, porcine lymphotropic herpesviruses, pseudorabies (Aujeszky's disease) virus

36 Influenza Viruses

37 Paramyxoviruses

Menangle virus, Nipah virus, porcine parainfluenza virus 1, porcine rubulavirus (blue eye paramyxovirus).

38 Porcine Parvoviruses

39 Pestiviruses

Atypical porcine pestivirus, border disease virus, bovine viral diarrhea virus, Bungowannah virus, classical swine fever virus.

40 Picornaviruses

Encephalomyocarditis virus, foot-and-mouth disease virus, porcine enteroviruses, porcine kobuvirus, porcine picornavirus Japan, porcine sapelovirus, porcine teschovirus, Seneca Valley virus, swine pasivirus, swine vesicular disease virus

41 Porcine Reproductive and Respiratory Syndrome Viruses (porcine arteriviruses)

42 Pox Virus

43 Reoviruses (Rotaviruses and Reoviruses)

44 Retroviruses

45 Rhabdoviruses

Rabies virus, vesicular stomatitis viruses

46 Togaviruses

Eastern equine encephalitis virus, Getah virus, Sagiyama virus, Ross River virus


47 Overview of Bacteria

Characteristics of genera, disease mechanisms, table of bacterial diseases. Issues in the development of bacterial disease (normal flora, biofilms, dysbacteriosis).

48 Actinobacillosis

Actinobacillus pleuropneumoniae - pleuropneumonia; Actinobacillus suis -- septicemia, pleuropneumonia; Actinobacillus equuli - septicemia.

49 Bordetellosis

Bordetella bronchiseptica - non-progressive atrophic rhinitis, bronchopneumonia.

50 Brucellosis

Brucella suis -- infertility, abortion, perinatal mortality.

51 Clostridiosis

Clostridium perfringens type C -- necrohemorrhagic enteritis; Clostridium perfringens type A -- enteritis; Clostridium dif icile -- necrotizing colitis; Clostridium septicum, perfringens type A, novyi, chauvoei -- cellulitis and gas gangrene; Clostridiium tetani - tetanus; Clostridiium botulinum - botulism.

52 Colibacillosis

Neonatal E. coli diarrhea, postweaning E. coli diarrhea and edema disease, E. coli causing fatal shock, systemic E. coli infections, coliform mastitis, nonspecific urinary tract infection.

53 Erysipelas

Erysipelothrix rhusiopathiae -- septicemia, arthritis, endocarditis; Erysipelothrix tonsillarum -- arthritis, endocarditis.

54 Glässer ́S Disease

Haemophilus parasuis -- fibrinous polyserositis and arthritis.

55 Leptospirosis

Leptospira spp. -- abortion and stillbirths.

56 Mycoplasmosis

Mycoplasma hyopneumoniae -- enzootic pneumonia; Mycoplasma hyorhinis -- polyserositis, arthritis; Mycoplasma hyosynoviae - arthritis; Mycoplasma (Eperythrozoon) suis - anemia.

57 Pasteurellosis

Pasteurella multocida -- progressive atrophic rhinitis, pneumonia, septicemia.

58 Porcine Proliferative Enteropathy

Lawsonia intracellularis -- acute proliferative hemorrhagic enteropathy (PHE), chronic porcine proliferative enteropathy (PPE).

59 Salmonellosis

Salmonella typhimurium, typhimurium I 1,4,[5],12:i:- variant, heidelberg, typhisuis -- enterocolitis; Salmonella choleraesuis var. kunzendorf -- septicemia, enterocolitis; Salmonella dublin, enteriditis -- meningitis.

60 Staphylococcosis

Staphylococcus hyicus -- exudative epidermitis; Staphyloccocus aureus -- skin infections, mastitis, others

61 Streptococcosis.

Streptococcus suis -- septicemia, meningitis, others; Streptococcus porcinus -- cervical lymphadenitis; Streptococcus dysgalactiae subsp. equisimilis -- septicemia, arthritis, others. Other streptococci -- various conditions. Enterococcus durans and hirae - diarrhea.

62 Swine Dysentery and Brachyspiral Colitis

Brachyspira hyodysenteriae, hampsonii, suanatina -- swine dysentery; Brachyspira pilosicoli -- intestinal (colonic) spirochetosis; Brachyspira intermedia, murdochii -- brachyspiral (mild) colitis.

63 Tuberculosis

Mycobacterium avium subsps. avium and hominissuis, M. bovis, M. caprae, M. tuberculosis -- localized alimentary lymphadentitis, rare disseminated tuberculosis.

64 Miscellaneous Bacterial Infections

Actinobaculum (Eubacterium) suis -- cystitis, pyelonephritis; Actinomyces hyovaginalis -- abortion, lung abscesses; Bacillus anthracis -- anthrax; Burkholderia pseudomallei -- melioidosis; Campylobacter spp. - enterocolitis; Chlamydia -- enteritis, pneumonia, abortion, etc.; Enterococci -- neonatal diarrhea; Klebsiella pneumonia -- septicemia; Listeria monocytogenes -- septicemia, encephalitis, abortion; Rhodococcus equi -- granulomatous lymphadenitis; Treponema pedis -- ear necrosis, other skin lesions; Trueperella abortisuis -- abortion; Trueperella pyogenes - pyogenic sepsis; Yersinia spp. -- enterocolitis.


65 External Parasites

Mange (Sarcoptes, Demodex), lice, fleas, mosquitoes, flies (myiasis), ticks.

66 Coccidia and Other Protozoa

Coccidia (Cystoisospora, Eimeria), Toxoplasma, Sarcocystis, Cryptosporidium, Giardia, microsporidia (Entercytozoon, Encephalitozoon), Balantidium coli, Entamoeba.

67 Internal Parasites: Helminths

Nematodes - Gongylonema, Hyostrongylus, Strongyloides, Ascaris, Trichinella, Trichuris, Oesophagostomum, Metastrongylus, Paragonimus, Stephanurus, and others; Cestodes - Echinococcus, Taenia, and others; parasiticides.


68 Nutrient Deficiencies and Excesses

Investigation of nutrient deficiencies or excesses, critical control points, inclusion rates, feed analysis, common nutrient concerns including amino acids, vitamins and minerals.

69 Mycotoxins in Grains and Feeds

Aflatoxin, ochratoxin, citrinin, trichothecenes (T2 toxin, DON), zearalenone, and fumonisins.

70 Toxic Minerals, Chemicals, Plants, and Gases

Minerals, feed additives, pesticides, toxic plants, nitrite, ef ects of water quality, toxic gases, and ventilation failure.

  • Idioma Inglés
  • Autor/es Locke A. Karriker
  • Año de edición 2019
  • Nº Páginas 1136
  • Encuadernación Tapa dura
  • Tamaño 22'1 X 28'4