Feline endocrinology

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Feline endocrinology

LANGUAGE: ENGLISH

Authors: Edward C. Feldman, Federico Fracassi, Mark E. Peterson
Release date: 2019
ISBN: 978-88-21448-37-9
Pages: 676
Binding: Hard cover
Format: 18,9 x 24,6

Developed by the most renowned experts in this field, this unique and practical handbook of feline endocrinology will be the most valuable tool for small animal veterinarians who want to deepen their understanding on the pathophysiology, clinical signs, diagnosis, treatment, and prognosis of every endocrine condition recognized in cats. Rather than have the authors treating cats as small dogs, a cat-only text will allow fully focused description of conditions in this one species. Allowing these experts in feline endocrinology space to fully teach us what they have learned about cats will result in a superior resource composed of text, figures, boxes, tables, algorithms, and videos (presented on an electronic version of the text).


143,27 €

136,11 €

Edward C. Feldman, DVM

DACVIM (Small Animal Internal Medicine)

Emeritus Professor of Small Animal Internal Medicine

University of California, Davis

Davis, California

USA

Federico Fracassi, DVM

DECVIM-CA (Internal Medicine)

Associate Professor of Small Animal Internal Medicine

Department of Veterinary Medical Sciences

University of Bologna

Italy

Mark E. Peterson, DVM

DACVIM (Small Animal Internal Medicine)

Animal Endocrine Clinic

New York, NY

Adjunct Professor of Medicine

Department of Clinical Sciences

Cornell University, College of Veterinary Medicine

Ithaca, NY

USA

SECTION 1 - HYPOTHALAMUS AND PITUITARY

Chapter 1 Pituitary anatomy and physiology
	Pituitary anatomy 
	Pituitary physiology 
	Hormones of the adenohypophysis (AL)
	Hormones of the neurohypophysis

Chapter 2 GH excess: acromegaly (hypersomatotropism)
	Background and history
	Incidence and pathogenesis
	Pituitary pathology
	Consequences of pituitary pathology
	Clinical features and diagnosis
	Treatment
	Prognosis

Chapter 3 Other pituitary tumors
	Pituitary masses: hyperplasia, adenoma or carcinoma?
	Incidence and cell origins of pituitary tumors
	Effect of pituitary tumors on target organs and the direct effects of large tumors
	Functional consequences of autonomous hormone production

Chapter 4 Pituitary surgery
	Introduction and general observations
	Surgical anatomy
	Imaging of the feline pituitary gland
	Pituitary adenomas
	Transsphenoidal hypophysectomy
	Postoperative care
	Complications after pituitary surgery
	Prognosis

Chapter 5 Pituitary irradiation 
	Introduction
	Clinical presentation
	Advanced imaging
	Role of radiation therapy
	Modalities of radiation therapy
	Nonfunctioning tumors
	Growth hormone-secreting pituitary tumors and acromegaly
	Adrenocorticotropic hormone-secreting pituitary tumors and feline Cushing’s disease
	Radiation-related adverse effects

Chapter 6 Pituitary GH deficiency and pituitary dwarfism
	Introduction
	Etiopathogenesis
	Clinical features
	Differential diagnosis for failure to grow
	Diagnosis
	Treatment

Chapter 7 Polyuria, polydipsia and diabetes insipidus
	Introduction
	Water requirements in healthy cats
	Urine concentrating ability in healthy cats
	Mechanisms of water retention
	Causes of polyuria and polydipsia in cats
	The diagnostic approach to polyuria and polydipsia
	Treatment of central diabetes insipidus
	Prognosis

SECTION 2 - THYROID GLAND

Chapter 8 Thyroid anatomy and physiology
	Anatomy of the feline thyroid gland
	General thyroid physiology
	Serum protein binding of thyroid hormones
	Hypothalamic-pituitary-thyroid axis
	Extrathyroidal metabolism of thyroid hormone
	Thyroid hormone kinetics in the cat
	Action of thyroid hormone

Chapter 9 Hyperthyroidism: background, etiopathogenesis and changing prevalence of feline thyroid disease
	History of thyroid disease in cats
	Studies into the etiopathology of feline hyperthyroidism
	Epidemiology of hyperthyroidism: a common worldwide disorder of senior to geriatric cats
	Why has feline nodular goiter reached such epidemic proportions?
	Conclusions

Chapter 10 Hyperthyroidism: clinical signs and physical examination findings
	Signalment
	Clinical signs
	Physical examination

Chapter 11 Hyperthyroidism: laboratory diagnosis
	Clinicopathologic abnormalities associated with hyperthyroidism
	Thyroid hormone abnormalities associated with hyperthyroidism
	Other diagnostic tests
	Conclusion

Chapter 12 Thyroid and kidney disease in cats
	Hyperthyroidism and chronic kidney disease (CKD)
	Effect of hyperthyroidism on serum test results of renal function
	Effect of hyperthyroidism on urinary markers of renal function
	Effect of hyperthyroidism on systolic blood pressure
	Effect of treatment of hyperthyroidism on renal function
	Effect of azotemia on how hyperthyroid cats are managed
	Suggested management strategies for hyperthyroid cats with CKD

Chapter 13 Thyroid imaging 
	Introduction
	Thyroid embryology, radiographic anatomy, and ectopic thyroid tissue
	Normal thyroid
	Hyperthyroidism
	Ectopic thyroid
	Thyroid carcinoma
	Thyroid cysts
	Hypothyroidism

Chapter 14 Treatment of hyperthyroidism: antithyroid drugs
	Considerations prior to initiating therapy with antithyroid drugs
	Mechanism of action of antithyroid drugs
	Formulations of antithyroid drugs
	Dosages of antithyroid drugs
	Adverse reactions with antithyroid drugs
	Monitoring cats treated with antithyroid drugs
	Other drugs of interest in managing hyperthyroid cats
	Success rate and survival in hyperthyroid cats managed with an antithyroid drug
	Renal function and hyperthyroidism
	Conclusion

Chapter 15 Treatment of hyperthyroidism: surgical thyroidectomy
	Introduction and overview
	Anatomy of the thyroid gland and surrounding structures
	Preoperative evaluation
	General anesthesia
	Feline thyroidectomy techniques
	Perioperative complications
	Postoperative recurrence of hyperthyroidism
	Surgical excision of thyroid adenocarcinoma
	Summary and conclusions

Chapter 16 Treatment of hyperthyroidism: radioiodine
	Introduction
	Advantages and disadvantages of radioiodine treatment of hyperthyroidism
	Principles of radioiodine treatment
	Specific indications for radioiodine treatment
	Patient selection and preparation before radioiodine treatment
	Thyroid scintigraphy for evaluation of hyperthyroid cats before 131I treatment
	Estimation of the radioiodine dose to administer to cats with hyperthyroidism
	Adverse effects or complications associated with radioiodine treatment
	Follow-up thyroid function testing after radioiodine treatment
	Prognosis after radioiodine treatment

Chapter 17 Treatment of hyperthyroidism: diet
	General nutritional assessment for the hyperthyroid cat
	Weight loss and muscle wasting
	Nutrients needed for the hyperthyroid cat
	Nutritional management of feline hyperthyroidism: feeding alow-iodine diet

Chapter 18 Treatment of hyperthyroidism: severe, unresponsive, or recurrent hyperthyroidism
	Introduction
	Etiology and pathogenesis of severe, unresponsive or recurrent hyperthyroidism
	Correlation between the severity and duration of hyperthyroidism and the severity of clinical signs
	Causes for treatment failure
	Therapy for severe, unresponsive hyperthyroidism
	Summary

Chapter 19 Hypothyroidism 
	Introduction
	Causes of hypothyroidism
	Clinical subtypes of hypothyroidism
	Naturally occurring, congenital hypothyroidism in kittens and junior cats
	Naturally occurring hypothyroidism in adult cats
	Iatrogenic hypothyroidism in adult cats
	Refractory hypothyroidism

SECTION 3 - CALCIUM AND PARATHYROID GLANDS

Chapter 20 Hypercalcemia
	Overview
	Calcium physiology 
	Laboratory testing
	Initial investigation in hypercalcemic cats
	Differential diagnosis of hypercalcemia

Chapter 21 Feline primary hypoparathyroidism and hypocalcemia
	Introduction
	Distribution of calcium in the body
	Control of calcium (Ca) homeostasis
	Hypocalcemia in people and dogs
	Hypoparathyroidism in cats
	Differential diagnosis of hypocalcemia
	Diagnostic testing
	Treatment

SECTION 4 - ADRENAL GLANDS

Chapter 22 Adrenal anatomy and physiology
	Adrenal anatomy
	Adrenal physiology

Chapter 23 Cushing’s syndrome (hypercortisolism)
	Introduction
	Etiology
	Clinical features
	Clinicopathological findings
	Endocrine testing
	Diagnostic imaging
	Treatment
	Prognosis

Chapter 24 Primary hyperaldosteronism (Conn’s syndrome)
	Introduction
	Primary hyperaldosteronism

Chapter 25 Other adrenal cortical tumors and pheochromocytoma
	Introduction and differential diagnosis
	Working up a feline adrenal mass
	Excessive progesterone production
	Combined excesses in progesterone and aldosterone
	Excessive androgen or estradiol production
	Pheochromocytoma
	Non-functional adrenal tumors

Chapter 26 Adrenal surgery via open and laparoscopic approaches
	Introduction
	Diagnostic evaluation
	Case selection
	Patient preparation
	Surgical techniques
	Post-operative care
	Complications

Chapter 27 Feline hypoadrenocorticism
	Introduction
	Prevalence
	Causes
	Age, breed and gender
	Clinical signs
	Clinical pathology
	Diagnostic imaging
	Electrocardiography and echocardiography
	Endocrine tests
	Differential diagnoses
	Treatment
	Prognosis

Chapter 28 Glucocorticoid therapy
	Physiology
	Pharmacology
	Therapeutic applications
	Adverse effects
	Glucocorticoid reduction protocol

SECTION 5 - ENDOCRINE PANCREAS

Chapter 29 Anatomy, histology and physiology of the feline endocrine pancreas
	Anatomy of the feline pancreas
	Cell types
	Cross-differentiation
	General function of islet hormones
	Secretory control
	Relative importance of pancreatic hormones and their contribution to the pathophysiology of diabetes mellitus
	Pancreatic amyloid as the most typical histological finding in diabetes mellitus

Chapter 30 Pathogenesis and clinical observations of uncomplicated diabetes mellitus
	Introduction
	Prevalence and epidemiology
	Risk factors
	Pathophysiologic mechanisms
	DM and pancreatitis 
	Clinical and laboratory findings
	Survival and prognostic factors

Chapter 31 Diabetic ketosis, ketoacidosis, and the hyperosmolar syndrome
	Introduction
	Glucose homeostasis
	Clinical presentation of DKA and HHS
	Principles of management of DKA and HHS
	Fluid and electrolyte therapy
	Insulin therapy
	Additional supportive therapy in DKA and HHS
	Prognosis of DKA and HHS in cats

Chapter 32 Insulin treatment of diabetes mellitus
	Aims of the treatment and management plan
	Insulin therapy
	Choosing an insulin
	Frequency of insulin administration, initial insulin dose and change in the type of insulin
	Storage, mixing and dilution of insulin
	Owner education
	Insulin dosing pens

Chapter 33 Gastrointestinal hormones and the use of non-insulin therapies for diabetes mellitus
	Introduction
	Incretin hormones physiology and pharmacology
	Metformin
	Glipizide
	Acarbose
	SGLT-2 antagonists
	Challenges in managing feline DM and potential uses of non-insulin therapies

Chapter 34 Dietary management for diabetes mellitus
	Overview 
	Learning outcomes
	Case 1: feeding cats that refuse or dislike their “diabetes diet”
	Case 2: an insulin overdosed diabetic cat that has just recovered from a severe “hypo” (neuroglycopenia)
	Case 3: non-prescription diet alternatives
	Case 4: achieving weight loss in a diabetic cat
	Case 5: managing diabetes in a cat with concurrent disease
	Case 6: the client has looked up a lot of information about diabetes in cats on the internet

Chapter 35 Monitoring diabetes in cats
	Clinical signs
	Blood glucose monitoring
	Continuous glucose monitoring systems (CGMS) and flash glucose monitoring systems
	Urine glucose measurement
	Fructosamine concentration
	Glycated hemoglobin

Chapter 36 Diabetic remission
	Definition of diabetic remission
	Physiology of diabetic remission
	Incidence of diabetic remission
	Predictors of diabetic remission
	Maximizing the likelihood of diabetic remission
	Identification and management of the diabetic cat in remission
	Prognosis and diabetic relapse
	Conclusions

Chapter 37 The unstable diabetic
	Overview
	Initial goals of therapy and factors that influence remission
	Classification of diabetes mellitus and relevance to unstable diabetic cats
	Inappropriate choice of insulin
	Inappropriate dosing
	Choice of intensive versus conservative insulin management of newly-diagnosed diabetics
	Client factors
	Underlying diseases
	Rebound hypoglycemia (Somogyi)
	The brittle diabetic
	Monitoring
	Other management strategies
	Conclusion

Chapter 38 Hypoglycemia
	Introduction
	Pathophysiology of hypoglycemia
	Blood glucose measurement
	Differential diagnoses
	Specific diseases or syndromes associated with hypoglycemia in cats
	Diagnostic approach
	Treatment of hypoglycemia

SECTION 6 - BLOOD PRESSURE, BODY CONDITION AND NUTRITION

Chapter 39 Feline obesity
	Epidemiology
	Pathophysiology of obesity
	Obesity-related diseases
	Treatment

Chapter 40 Disorders of lipid metabolism
	Introduction
	The basics of lipoprotein metabolism
	Definitions and measurement of feline serum lipid concentrations
	Effect of lipemia on the measurement of other analytes
	Causes of feline hyperlipidemia
	Clinical consequences of hyperlpidemia in cats
	Diagnostic approach to cats with hyperlipidemia
	Treatment of feline hyperlipidemia

Chapter 41 Cachexia and sarcopenia
	Cachexia
	Sarcopenia
	Diagnosis of cachexia and sarcopenia
	Potential interventions for cachexia and sarcopenia
	Practical approach to treatment of cachexia and sarcopenia in cats
	Conclusion

Chapter 42 Hypertension
	Introduction
	Measurement of blood pressure incats
	Defining hypertension and deciding when to treat
	Consequences of hypertension
	Endocrine causes of hypertension
	Management of hypertension
	Annex Conversion tables
	Conversion to Systeme International (SI) Units

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Feline endocrinology

Feline endocrinology

LANGUAGE: ENGLISH

Authors: Edward C. Feldman, Federico Fracassi, Mark E. Peterson
Release date: 2019
ISBN: 978-88-21448-37-9
Pages: 676
Binding: Hard cover
Format: 18,9 x 24,6

Escribe tu opinión

Escribe tu opinión

Feline endocrinology

Feline endocrinology

LANGUAGE: ENGLISH

Authors: Edward C. Feldman, Federico Fracassi, Mark E. Peterson
Release date: 2019
ISBN: 978-88-21448-37-9
Pages: 676
Binding: Hard cover
Format: 18,9 x 24,6

Escribe tu opinión

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