Immunosuppresive diseases of poultry
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Immunosuppresive diseases of poultry

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The goal of this work is to present the reader with the most common diseases that can produce immunosuppression in poultry, provide guidance for the diagnosis of immunosuppressive diseases, and examine the challenges that a diagnostician may face in confirming a diagnosis of immunosuppression. The book will feature an extensive collection of color photographs depicting the gross and microscopic images.

Isabel M. Gimeno

Licenciada en Veterinaria (DVM equivalent) - Universidad Complutense de Madrid, 1995. PhD - Universidad Complutense de Madrid, 1999. MS - Universidad Complutense de Madrid, 1996. Associate Professor, Poultry Health Management. Diplomate, American College of Poultry Veterinarians.

July 2012 to present. Associate Professor. Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University.

February 2006 to July 2012. Assistant Professor. Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University.

February 2002 to January 2006. Postdoctoral position at the USDA-ARS Avian Disease and Oncology Laboratory, East Lansing, MI.

January 2001 to January 2002 . Research Associate at the Animal Health Diagnostic Laboratory, Michigan State University, East Lansing, MI.

January 2000 to December 2000. Research Associate at the Research Institute for Animal Health (CISA-INIA), Valdeolmos, Madrid.

Areas of Research/Study:

  • Avian tumor viruses.
  • Avian herpesviruses.
  • Emerging poultry infectious diseases.
  • Poultry immunology.
  • Poultry pathology.

1. Introduction: Histopathology of Immunosuppression in Chickens

OSCAR J. FLETCHER

Introduction

Lesion scoring

Bursa of Fabricius

Thymus

Spleen

Morphometry

Bursa of Fabricius (BF)

Thymus

Spleen

Conclusions

References

2. Non-infectious causes of immunosuppression: Mycotoxins and Stress

ENRIQUE MONTIEL Y ORLANDO OSUNA

Mycotoxins and immunosuppression

Introduction

Etiology

Epidemiology

Aflatoxins

Clinical signs of aflatoxicosis

Gross lesions of aflatoxin

Histopathology of aflatoxin

Effect of aflatoxin on the immune system of

poultry

Diagnosis of aflatoxin

Differential diagnosis

Ochratoxin A (OTA)

Clinical signs of ochratoxicosis

Gross lesions of ochratoxin A (OTA)

Histopathology of ochratoxin A (OTA)

Effect of OTA on the poultry immune

system

Diagnosis of ochratoxicosis

Differential diagnosis

Citrinin

Oosporein

Fusarium toxins

Fumonisins

Trichothecenes

References

Stress and immunosuppression

Introduction

The connection between stress, immunosuppression and decreased performance

Understanding stress

Measuring stress or immunosuppression?

Stress and poultry practice

References

3. Virus-induced immunosuppression:

Infectious Bursal Disease

NATÀLIA MAJÓ Y ROSER DOLZ

Introduction

The etiological agent: Infectious Bursal

Disease Virus

Taxonomy and genome organization

Viral structure and proteins

Cell infection, genome replication and transcription

Virus properties

IBDV antigenicity and immunogenicity

IBDV pathogenicity

IBDV genetic diversity

Epidemiology

Hosts and transmission

Geographic distribution of IBDV

Pathogenesis and host immune response

Immunosuppression

Clinical signs

Gross and microscopic lesions

Diagnosis

Viral detection

Antibody detection

Prevention and control

Inactivated vaccines

Conventional live attenuated virus vaccines

Vector vaccines

Immune complex vaccines

References

4. Virus-induced immunosuppression: Chicken Infectious Anemia

JOAN A. SMYTH Y KAREL A. SCHAT

Introduction

Etiology

Virus structure, composition and classification

Classification

Stability

Epidemiology

Host range

Geographical distribution

Transmission

Pathogenesis

Clinical signs

Pathology

Embryos

Chickens

CAV-induced immunosuppression

Effect of infection on cell populations

Effect of infection on macrophage activity and cytokine production

Economic effects

Economic effects of clinical CAV induced disease

Economic effects of subclinical disease

Interactions with other Infectious Agents

CAV and infectious bursal disease virus

CAV and tumor viruses

CAV, reovirus and adenovirus

CAV and respiratory infections

CAV and bacteria or fungi

Diagnosis

General

Blood testing

Examination of diseased chickens

Control and prevention of CAV infection and disease

General

Vaccination using currently available vaccines

Experimental vaccines, and novel approaches to CAV vaccination

Treatment

References

5. Virus-induced immunosuppression: Marek’s Disease Virus infection and associated syndromes

ISABEL M. GIMENO Y ARUN R. PANDIRI

Introduction

Etiology

Epidemiology

Pathogenesis

MDV-induced syndromes

Non-neoplastic syndromes

Neoplastic syndromes (tumors)

MDV immunosuppression (MDV-IS)

References

6. Virus-induced immunosuppression: Reticuloendotheliosis and other

immunosuppressive viruses

GUILLERMO ZAVALA

Introduction

Etiology

Classification

Nucleic acids and chemical composition

Virus replication

Epidemiology

Host range

Geographical distribution

Transmission

Transmission in commercial flocks

Transmission in nature

Pathogenesis

Clinical signs

Pathology

Gross pathology

Microscopic pathology

Immunosuppression

Impairment of leukocyte blastogenesis

Disturbances in immune regulation

Immune responses to avian pathogens

Economic effects

Interactions with other Infectious Agents

Diagnosis

Vaccination

Treatment

References

9788494138959
  • Language English
  • Author/s Isabel M. Gimeno Presa, y otros
  • Release date 2013
  • Pages 192
  • Binding Hard cover
  • Dimensions 22 X 28

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