This book presents, in a rationale and practical manner, the main facts that veterinary students and professionals should know in order to deal with PCV2 and related diseases. Besides general knowledge on the virus and pathogenesis, major emphasis is focused on the immunity, diagnosis and proper use of vaccines. Noteworthy, epidemiology, clinical signs and lesions are fundamental cornerstones to revisit. The author is one of the most prolific researchers on PCVD. He has contributed greatly in terms of expanding knowledge and has laid the foundation for further progress and knowledge of the virus and the associated diseases, thus creating an original and at the same time consistent book with the scientific state of the art.