A guide to oncology for veterinary clinicians
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A guide to oncology for veterinary clinicians

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This Guide to Oncology for Veterinary Clinicians compiles practical information to aid veterinary clinicians in managing cancer patients, and covers aspects related to diagnosis, prognosis, and treatment, as well as pain management and communication with owners. It has been developed by leading specialists in oncology who approach the subject from a practical perspective, and includes many images, tables, and diagrams that facilitate understanding of its content and make it an essential volume on the bookshelves of any veterinary clinic.

Noemí del Castillo Magán

Noemí del Castillo Magán graduated in veterinary medicine from the Complutense University of Madrid (UCM), Spain, in 1997 and earned a PhD in veterinary medicine from the same university in 2002. She is certified in veterinary oncology by the Spanish Small Animal Veterinary Association (AVEPA). She has been a professor at the Small Animal Internal Medicine and Anatomical Pathology Department at Alfonso X El Sabio University (UAX) in Madrid since 2005. She is also head of the Oncology Department at the UAX Veterinary Teaching Hospital. In 2004, Noemí joined the Surbatán veterinary clinic as partner and she now heads the Oncology Unit at this practice. She is a founding member of the scientific committee of GEVONC-AVEPA (Group of Veterinary Oncology Specialists of AVEPA), a member of the European Society of Veterinary Oncology (ESVONC), and an honorary member of the Latin American Society of Veterinary Oncology (SLOVET). She has authored and coauthored numerous articles in national and international journals, published chapters in several books, and presented papers at oncology conferences in Spain and abroad.

Ricardo Ruano Barneda

Ricardo Ruano Barneda graduated in veterinary medicine from the UCM in 1999 and is an AVEPA-certified oncology specialist. He is a veterinary surgeon at the Mediterráneo veterinary hospital in Madrid, where he is head of the laboratory and the Oncology Department. He is a founding member of the scientific committee of GEVONC-AVEPA and a member of ESVONC. Ricardo has authored a book on practical small animal oncology Oncología práctica para el clínico de pequeños animales (Practical Oncology for Small Animal Clinicians; ed. Multimédica Ediciones Veterinarias) and published papers in Spanish and international journals and chapters in several books. He has also presented work at oncology conferences.

Collaborators

Elena Martínez de Merlo

Elena Martínez de Merlo graduated in veterinary medicine from the UCM in 1987 and earned a PhD in veterinary medicine from the same university in 1993. She has worked as a professor at the UCM’s Department of Medicine and Animal Surgery since 1998. She is a veterinary surgeon at the UCM Veterinary Teaching Hospital (HCVC), where she heads the Oncology and Cytology Diagnosis Units within the Clinical Biopathology Department. She has published two books: Atlas de citología clínica del perro y del gato (An Atlas of Clinical Cytology in Dogs and Cats) (ed. Servet, 2008) and Manual práctico de oncología en pequeños animales (A Practical Small Animal Oncology Manual) (ed. Axón Comunicación, 2011 and 2014). Elena is director of the Continuous Education Diploma in Cytological Interpretation in Small Animals at the UCM, a course which is now in its 10th edition. She is an AVEPA-certified oncology specialist and a member of GEVONC, of which she is a former president. She has presented conference papers both in Spain and internationally and given numerous courses, talks, and practical workshops on oncology and cytological diagnosis. Finally, Elena has authored and coauthored articles on oncology and the application of cytological diagnosis to clinical settings in Spanish and international journals.

Isabel del Portillo Miguel

Isabel del Portillo Miguel graduated in veterinary medicine from the UAX in 2011, where she also participated in a 1-year internship programme and a 2-year residency programme. She joined the UAX’s Oncology Department in 2012. She has been a staff member at the Aúna Especialidades Veterinarias veterinary clinic since December 2016. She holds a master’s degree in clinical oncology from the Spanish Association of Applied Veterinary Medicine (AEVA) and is currently completing her doctoral thesis on the use of oncolytic viruses in the treatment of spontaneous tumours in dogs.

Josep Pastor Millán

Josep Pastor Millán graduated in veterinary medicine from the Autonomous University of Barcelona (UAB) in 1989 and obtained a PhD in veterinary medicine from the same university in 1994. He has been a professor at the UAB’s Department of Animal Medicine and Surgery since 1991, a job he combines with clinical work at the university’s Veterinary Teaching Hospital. He is a Diplomate of the European College of Veterinary Clinical Pathology (ECVCP). His areas of interest are haematology and small animal oncology.

Jorge Azcárate Mengual

Jorge Azcárate Mengual graduated in veterinary medicine from the UCM in 1990. He is head of the Diagnostic Imaging Unit of the Mediterráneo veterinary hospital and teaches practical skills at the UCM Veterinary Teaching Hospital.

Ángel Sainz Rodríguez

Ángel Sainz Rodríguez graduated in veterinary medicine from the UCM in 1991 and earned a PhD in veterinary medicine from the same university in 1996. He is a professor in the Department of Medicine and Animal Surgery at the Faculty of Veterinary Medicine of the UCM. He is AVEPA-certified in internal medicine. Ángel has also furthered his training at different centres, including the Veterinary Teaching Hospital at the University of Illinois in Urbana-Champaign, USA. His areas of interest are gastroenterology and endoscopy in small animals and vector-borne diseases, in particular ehrlichiosis and canine leishmaniasis. He is a staff member at the HCVC’s Small Animal Internal Medicine Department (specialising in gastroenterology and endoscopy) and head of the Ehrlichiosis Diagnostic Department at the UCM’s Faculty of Veterinary Medicine.

Fernando Rodríguez Franco

Fernando Rodríguez Franco earned a degree in veterinary medicine and a PhD in veterinary medicine from the UCM in 1983 and 1990. He has worked as a professor in medicine and animal surgery since 1991 and is head of the Small Animal Gastroenterology and Endoscopy Service at the HCVC. Fernando has been head of the UCM’s Animal Medicine and Surgery Department since 2010. He is AVEPA-certified in small animal internal medicine and has published over 90 journal articles and given numerous presentations at Spanish and international congresses. His current research focuses on digestive oncology in small animals and the diagnosis and medical and dietary treatment of chronic immune-mediated digestive disorders.

Andrés Calvo Ibbitson

Andrés Calvo Ibbitson graduated in veterinary medicine from the UCM in 2000. He was a member of the Histology and Anatomical Pathology Department at the UCM’s Faculty of Veterinary Medicine from 2001 to 2006, and is currently head pathologist at Citopath Veterinaria. He lectures in histology and anatomical pathology at the UAX’s Faculty of Veterinary Medicine.

Ana Cloquell Miró

Ana Cloquell Miró graduated in veterinary medicine from the UAX in 2008. She completed a 1-year internship programme and a 2-year residency programme at this university, where she was active in the Oncology and Neurology Departments. In 2012, she joined the Neurology Department at the UAX’s Veterinary Teaching Hospital. Ana has been a resident at the European College of Veterinary Neurology since February 2016. She also teaches neurology-related classes as part of the UAX’s Pathophysiology, Diagnostic Imaging, and Clinical Examination modules.

Víctor Domingo Roa

Víctor Domingo Roa graduated in veterinary medicine from the University of Córdoba, Spain, in 2002 and has worked as a small animal veterinary surgeon at the Recuerda veterinary clinic in Granada since 2003. His areas of interest are internal medicine and oncology. He received certification as an oncology specialist from AVEPA in 2013. In 2005, he joined the Tumour Biomarker Research Group at the University of Córdoba, where he obtained his PhD in veterinary medicine. He is a member of ESVONC and a founding member of the scientific committee of GEVONC-AVEPA. He has been head of the Oncology Department at the Hospital Veterinario Sur in Granada since 2014 and in 2015 he joined the Radiotherapy Department at the Centro Integral de Oncología Veterinaria (Cabra, Córdoba), as a veterinary oncology surgeon.

Ignacio Sández Cordero

Ignacio Sández Cordero graduated in veterinary medicine at the UCM in 2000. He is AVEPA-certified in anaesthesia and analgesia. He is also the founder of Sinergia Veterinaria, a company of mobile veterinary specialists that offers services to over 400 veterinary practices and hospitals, mainly in the Community of Madrid. He has headed the Anaesthesiology Department at Sinergia Veterinaria since its creation. Ignacio is a founding member of the Spanish Society of Veterinary Anaesthesia and Analgesia (SEAAV) and served on its board until June 2012. He is currently a member of the board of directors of veterinary specialties at AVEPA. Ignacio has given anesthaesia courses, practical workshops, and online training since 2005 and published over 20 articles on anesthaesia, analgesia, and reanimation in small species in specialist magazines in Spain (Consulta, Pequeños Animales, Argos, Centro, etc.) and in specialist online media with an international scope (veterinaria.org, Portal Veterinario). Finally, he has given talks and presented posters at different editions of the National SEAVV Conference.

1. Dealing with a patient with a mass: client communication

Introduction

Breaking the news and dealing with the consequences

Dispelling fears and myths

Staff training

Losing a pet

Quality of life

Compassion fatigue

2. Recognising signs consistent with cancer in senior pets

Signs of oral cancer

Signs of skin cancer

Cats

Dogs

Signs of abdominal tumours

Cats

Dogs

Other signs of cancer

Age-related changes in different body systems

Diagnosis and prognosis in veterinaryoncology

3. Diagnostic procedures in veterinary oncology

Cytology

Introduction

Sample collection, slide preparation, and staining

Cell interpretation protocol

Biopsy

Blood and bone marrow smears

Flow cytometry and PCR for antigen receptor rearrangements

The importance of immunophenotyping in canine lymphoma

Flow cytometry

PCR for antigen receptor rearrangements

Diagnostic imaging in veterinary oncology

Radiography

Ultrasound

Computed tomography

Magnetic resonance imaging

Endoscopy

Gastrointestinal endoscopy

Airway endoscopy

Endoscopy in other locations

General state of senior patients.

Laboratory tests

Clinical staging:

TNM staging system

4. Diagnostic interpretation, choice of treatment, and prognosis

Cytology

Cytological assessment of cell lineage

Assessment of cytological criteria for malignancy

Cytological characteristics of main tumours

Biopsy

What is tumour grade?

Tumour margins

Special stains

Biological behaviour of tumours according to tissue of origin

Epithelial tumours

Mesenchymal tumours

Haematopoietic tumours

Other origins

Biological behaviour of tumours according to location

Cutaneous and subcutaneous tumours

Head, neck, and ear tumours

Chest cavity tumours

Tumours of the reproductive system

Abdominal cavity tumours

Nervous system tumours

Skeletal tumours

Haematopoietic tumours

5. Cancer treatment

Surgery

Introduction

Indications

Chemotherapy

Indications

Resistance

Handling of cytostatics

Classification of anticancer drugs

Adverse effects of chemotherapy

Radiation therapy

Principles of radiobiology

Equipment

Indications

Adverse effects

Antiangiogenic therapy

Tyrosine kinase inhibitors

Biology

Kinase inhibition

Immunotherapy

Biological response modifiers

Recombinant cytokines

Antitumour vaccines

COX-2 inhibitors

6. Pain in veterinary oncology

Evaluating pain in a patient with cancer

Signs of pain

Pain treatment

Why treat and when?

Classification of analgesics

New analgesic techniques

Analgesic treatment during oncological surgery

7. Appendices

Appendix I. Paraneoplastic syndromes

Haematological disorders

Metabolic, digestive, and endocrine-related disorders

Cutaneous disorders

Other

Appendix II. Treatment protocols

Canine lymphoma

Feline lymphoma

Canine haemangiosarcoma/

Soft tissue sarcoma

Multiple myeloma

Canine mast cell tumour

Carcinomas in dogs

Carcinomas and sarcomas in cats

Osteosarcoma in dogs

Appendix III. Metronomic therapy

Appendix IV. Survival data for nervous system tumours

8. References

9788417225421
  • Autor/es Noemí del Castillo Magán, Ricardo Ruano Barneda
  • Fecha de edición junio 2018
  • Nº Páginas 192
  • Encuadernación Tapa dura
  • Tamaño 22 X 28
  • Idioma Inglés

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