The aim of this book is to focus on problems unique to the feline alimentary tract in comparison to dogs and to discuss them in detail, but also to highlight areas where knowledge is lacking or can only be derived from comparison with other companion animal species or humans. Instead of being a comprehensive work of all things GI in the cat, this book aims to shine a light on topics that are novel, such as the microbiome or probiotics, and might not have been covered by other standard textbooks. This book focuses on a medics perspective on feline alimentary tract health, which starts with considering differential diagnoses in a structured way based on the most common clinical signs. It also includes the invaluable input from other specialties we so often draw on in clinical practice, namely laboratory diagnostics, diagnostic imaging, clinical pathology and histopathology, and nutrition, which can be a particular challenge in cats. It also covers feline-specific infectious and neoplastic diseases. Appropriate methods for retrieving adequate samples from organs of the alimentary tract in cats are discussed, and a particular focus on the challenges of differentiating inflammation from neoplasia is present in several chapters. Extra materials and videos are available.