This handbook is entirely dedicated to avian salmonellosis based on a handy and visual approach of the topic. Being a critical public health issue, avian salmonellosis is a very important condition that should be acquainted for, controlled and prevented by every veterinary surgeon involved in the poultry industry. A handbook like this will help the experts understand, diagnose, treat and control this disease and thus contribute to maintain the animals’ and the final consumers’ optimum health status. Vaccination procedures are well described in order to provide the main guidelines to avoid vaccination failures and help controlling the prevalence and incidence. Issues like management control and biosecurity are also included to complete this practical guide on avian salmonellosis.